Dynamic Gene Regulatory Networks of Human Myeloid Differentiation
نویسندگان
چکیده
منابع مشابه
Dynamic Gene Regulatory Networks of Human Myeloid Differentiation.
The reconstruction of gene regulatory networks underlying cell differentiation from high-throughput gene expression and chromatin data remains a challenge. Here, we derive dynamic gene regulatory networks for human myeloid differentiation using a 5-day time series of RNA-seq and ATAC-seq data. We profile HL-60 promyelocytes differentiating into macrophages, neutrophils, monocytes, and monocyte-...
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ژورنال
عنوان ژورنال: Cell Systems
سال: 2017
ISSN: 2405-4712
DOI: 10.1016/j.cels.2017.03.005